Who we are
Welcome to Marcelo Nollmann's research group at the Center for Structural Biochemistry- CNRS/INSERM in Montpellier, France. We develop single-molecule and advanced microscopy methodologies to investigate the mechanisms underlying DNA segregation and organization.
June'17: Diego, Andres and Mariya had their paper online in BioRxiv: Single-cell absolute contact probability detection reveals that chromosomes are organized by modulated stochasticity
Dec '16: We have just been awarded an ERC consolidator Grant!
Nov '16: Jean-Bernard, Laura and Leon published their paper in Nature! <More news>
Molecular dissection of bacterial gliding
We deciphered the mechanism by which Myxococcus Xhantus glide on surfaces using a revolutionary combination of advanced microscopies and microfluidics.
Faure, et al. Nature (2016)
3D localization microscopy over 4µm depth
We combined multifocus microscopy with single-molecule localization to image cells at super-resolution over 4µm
Oudjedi, Biom. Optics Express (2016)
Plasmid segregation super-resolved
We used super-resolution and multifocus microscopies to show that plasmids segregate through bacterial nucleoids by the action of ParA and by relying on the host chromosome scaffold
Le Gall, et al. Nature Comm (2016)
Assembly of bacterial partition systems
Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus
Sanchez, et al., Cell Systems (2015)
Bacterial chromosome structure
Condensin- and replication-mediated dynamic folding of a bacterial chromosome and its origin domain revealed by super-resolution imaging and Hi-C
Marbouty, et al. Mol Cell (2015)
Assembly and mechanism of a DNA pump
Recruitment, Assembly, and Molecular Architecture of the SpoIIIE Revealed by Superresolution Microscopy.
Fiche, et al., PLoS Biology (2013)
A complete list of publications, excluding chapters and articles not accessed by PubMed, can be found here.